If you’ve recently learned that you have the "bad" form of the MTHFR gene (like C677T or A1298C), you’re not alone — and you’re not broken. This common genetic mutation affects how your body processes folate, detoxes toxins, and even regulates mood. But with the right support, you can feel amazing and thrive.

🌿 What Is MTHFR?

MTHFR stands for methylenetetrahydrofolate reductase, an enzyme that helps your body convert folate (vitamin B9) into its usable form: L-methylfolate (5-MTHF). If you have a mutation in this gene, your body struggles to do this efficiently, which can impact:

• Detox pathways (especially in the liver)

• Mood and neurotransmitter balance (like serotonin and dopamine)

• Hormone regulation

• Energy production

• Cardiovascular health

• Methylation (your body’s “on/off switch” for many critical functions)

🚫 Why Folic Acid Is a No-Go

If you have MTHFR, synthetic folic acid (the form in most supplements and fortified foods) can actually make things worse. Your body can’t process it efficiently, and it may build up in your system, blocking receptors and contributing to:

• Fatigue

• Brain fog

• Mood swings or anxiety

• Poor detox

• B12 masking or deficiencies

Instead, look for L-5-MTHF (methylfolate) and methylated B12 (methylcobalamin) — these are already in their active forms and ready to be used by your body.

💊 Core Supplements for MTHFR Support

Here’s a foundational list of supplements that are safe and supportive for people with MTHFR:

• Methylated B-complex (with methylfolate, methyl B12, P-5-P, and riboflavin)

• Magnesium glycinate or threonate (for nervous system and detox)

• L-Tyrosine (for dopamine support, especially if you take stimulants)

• Vitamin C (antioxidant and liver support)

• NAC (N-acetyl cysteine) (boosts glutathione, detox support)

• Omega-3s, CoQ10, Milk Thistle, and adaptogens (optional but helpful)

These work best when taken consistently and at the right times (e.g., B vitamins in the morning, magnesium in the evening, NAC on an empty stomach).

⚠️ What to Avoid

• Synthetic folic acid (in vitamins and fortified foods)

• Processed food with additives

• Overuse of Tylenol or alcohol

• High doses of synthetic multivitamins or energy drinks

🧠 MTHFR + Adderall: What You Should Know

If you take Adderall and have MTHFR, you may have a higher need for nutrients like B12, magnesium, and antioxidants. Stimulants increase your body's methylation demand and can deplete key vitamins — but with the right support (like the stack above), many people do just fine.

Focus on:

• Methylated B-complex (daily)

• Magnesium (night)

• L-Tyrosine (morning)

• NAC or Milk Thistle (liver support)

Work with a provider who understands both MTHFR and ADHD/stimulant metabolism.

🍵 Herbal Teas to Support MTHFR (and Make It All a Little More Delicious)

Herbs can be incredibly supportive for the nervous system, liver, and overall balance — especially when you have MTHFR. At Urbll, we create blends with these needs in mind. Here are some of our favorites:

• Nettle Leaf – Naturally rich in folate and iron, supports detox and energy

• Dandelion Root – Gently stimulates the liver, supports bile flow

• Tulsi (Holy Basil) – Adaptogenic, calming, and great for hormone + stress balance

• Lemon Balm – Helps with nervous system regulation and mood support

• Blue Lotus – Calms the mind, supports clarity, and pairs beautifully with meditation or winding down

🛠 Final Tips for Living Well with MTHFR

• Stick with whole, organic foods as much as possible

• Hydrate with trace minerals or lemon water

• Move daily (even gently)

• Get enough sleep to help your body repair and detox

• Take time to de-stress and unwind (herbal baths, teas, nature walks — they all help)

MTHFR isn’t a sentence — it’s simply a reminder to be more intentional with how you nourish and care for your body. And we’re here for that journey.

🌿 Shop MTHFR-friendly herbal teas and wellness blends at urbll.com or urbll.etsy.com